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Afuresertib HCl

Reference Materials
Item No.CFZ1284
CAS Number:1047645-82-8
Purity:98%
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Basic information and product description
CAS number
1047645-82-8
Item number
CFZ1284
Chinese name
Afuresertib HCl
English name
Afuresertib HCl
Chinese alias
N-((S)-1-氨基-3-(3-氟苯基)丙-2-基)-5-氯-4-(4-氯-1-甲基-1H-吡唑-5-基)噻吩-2-甲酰胺盐酸盐
English alias
N-((S)-1-Amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride
SMILES
Chemical name
Molecular formula
C₁₈H₁₈Cl₃FN₄OS
Molecular weight
463.78
Purity
98%
Delivery
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Product Description

Afuresertib hydrochloride (GSK 2110183 hydrochloride) 是一个口服有效的，ATP 竞争性的选择性 pan-Akt 抑制剂，作用于 Akt1/Akt2/Akt3，Ki 值分别为 0.08/2/2.6 nM。 

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