GSK 3008348

Item No.CFZ01262

CAS Number:1629249-33-7

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

Application of bioactive small molecules in disease research

Green intelligence creates industry trends, Fuzhen Biology promotes low-carbon development of fine chemical industry

The monoclonal antibody industry is developing rapidly, and Fuzhen Biotechnology is improving its supply system for monoclonal antibody related raw materials

The global biopharmaceutical market continues to expand

Molecular building blocks are used as accelerators for the development of new drugs

Basic information and product description

CAS number

1629249-33-7

Item number

CFZ01262

Chinese name

GSK 3008348

English name

GSK 3008348

Chinese alias

(βS,3R)-β-[3-(3,5-二甲基 -1H-吡唑 -1-基) 苯基]-3-[2-(5,6,7,8-四氢 -1,8-萘啶 -2-基) 乙基]-1-吡咯烷基丁酸

English alias

SMILES

Chemical name

Molecular formula

C₂₉H₃₇N₅O₂

Molecular weight

487.64

Purity

98%

Delivery

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Product Description

GSK 3008348 是一种针对整合素 αvβ6 的小分子拮抗剂，其对于 αvβ6、αvβ1、αvβ3、αvβ5、αvβ8 的 IC50 值分别为 1.50、2.83、12.53、4.00 和 2.26 nM。GSK 3008348 能够靶向 αvβ6 整合素，抑制 TGF-β 的激活，从而缓解纤维化过程。GSK 3008348 可阻断口蹄疫病毒与宿主细胞表面受体 αvβ6 整合素的结合，从而抑制病毒进入GSK 3008348 可用于肺纤维化及多种癌症的研究。

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GSK 3008348

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