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AK2292

Reference Materials
Item No.CFZ01416
CAS Number:2984506-77-4
Purity:98%
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Basic information and product description
CAS number
2984506-77-4
Item number
CFZ01416
Chinese name
AK-2292
English name
AK2292
Chinese alias
English alias
SMILES
Chemical name
Molecular formula
C₅₂H₅₄F₂N₇O₁₀PS₂
Molecular weight
1070.13
Purity
98%
Delivery
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Product Description

AK-2292 是一种有效和选择性 STAT5 PROTAC 降解剂，DC50 值为 0.10 μM。AK-2292 在体外和体内诱导 STAT5A/B 蛋白的降解。AK-2292 可在急性髓性白血病和慢性髓性白血病异种移植小鼠模型中诱导肿瘤消退。

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