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LY2835219

Reference Materials
Item No.CFZ01380
CAS Number:1231930-82-7
Purity:98%
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Basic information and product description
CAS number
1231930-82-7
Item number
CFZ01380
Chinese name
LY2835219甲磺酸盐
English name
LY2835219
Chinese alias
N-[5-[(4-乙基-1-哌嗪基)甲基]-2-吡啶基]-5-氟-4-[4-氟-2-甲基-1-异丙基-1H-苯并咪唑-6-基]-2-嘧啶胺甲烷磺酸盐
English alias
N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate
SMILES
Chemical name
Molecular formula
C₂₈H₃₆F₂N₈O₃S
Molecular weight
602.7
Purity
98%
Delivery
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Product Description

Abemaciclib methanesulfonate (LY2835219 methanesulfonate) 是选择性和能透过血脑屏障的 CDK4/6 抑制剂，抑制 CDK4/CDK6 的 IC50 分别为 2 nM 和 10 nM。 

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