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SIS3

Reference Materials
Item No.CFZ01365
CAS Number:521984-48-5
Purity:98%
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Basic information and product description
CAS number
521984-48-5
Item number
CFZ01365
Chinese name
SIS3 hydrochloride
English name
SIS3
Chinese alias
(E)-1-(6,7-二甲氧基-3,4-二氢异喹啉-2(1H)-基)-3-(1-甲基-2-苯基-1H-吡咯并[2,3-b]吡啶-3-基)丙-2-烯-1-酮 盐酸盐
English alias
(E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one hydrochloride
SMILES
Chemical name
Molecular formula
C28H28ClN3O3
Molecular weight
489.99
Purity
98%
Delivery
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Product Description

SIS3 是一种有效和选择性的 Smad3 抑制剂，抑制 Smad3 磷酸化的 IC50 为 3 μM。SIS3 通过 TGF-β1 抑制成纤维细胞向肌成纤维细胞分化。

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