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Icenticaftor

Reference Materials
Item No.CFZ01344
CAS Number:1334546-77-8
Purity:98%
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Basic information and product description
CAS number
1334546-77-8
Item number
CFZ01344
Chinese name
Icenticaftor
English name
Icenticaftor
Chinese alias
3-氨基 -6-甲氧基-N-[(2S)-3,3,3-三氟 -2-羟基 -2-甲基丙基]-5-(三氟甲基)-2-吡啶甲酰胺
English alias
Icenticaftor
SMILES
Chemical name
Molecular formula
C12H13F6N3O3
Molecular weight
361.24
Purity
98%
Delivery
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Product Description

Icenticaftor (QBW251) 是一种具有口服活性 CFTR 通道增强剂，F508del 和 G551D CFTR 的 EC50 分别为 79 nM 和 497 nM。Icenticaftor 可用于慢性阻塞性肺疾病 (COPD) 和囊性纤维化研究。 

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