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BML-210

Reference Materials
Item No.CFZ01229
CAS Number:537034-17-6
Purity:98%
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Basic information and product description
CAS number
537034-17-6
Item number
CFZ01229
Chinese name
BML-210
English name
BML-210
Chinese alias
N1-(2-氨基苯基)-N8-苯基辛二酰胺
English alias
N1-(2-Aminophenyl)-N8-phenyloctanediamide
SMILES
Chemical name
Molecular formula
C₂₀H₂₅N₃O₂
Molecular weight
339.43
Purity
98%
Delivery
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Product Description

BML-210 是一种有效的 HDAC 抑制剂。BML-210 可以抑制 HDAC4-VP16 驱动的报告信号,IC50 为 ~5 µM。BML-210 对 HDAC4:MEF2 交互具有特定的破坏性影响。BML-210 导致 G0/G1 期增加。BML-210 诱导细胞凋亡,并在小鼠原位乳腺肿瘤中显示出抗肿瘤活性。 

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