Marein

Item No.CFZ08417

CAS Number:535-96-6

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

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Basic information and product description

CAS number

535-96-6

Item number

CFZ08417

Chinese name

马里苷

English name

Marein

Chinese alias

English alias

Okanin-4'-O-glucoside;

SMILES

C1=CC(=C(C=C1C=CC(=O)C2=C(C(=C(C=C2)OC3C(C(C(C(O3)CO)O)O)O)O)O)O)O

Chemical name

Molecular formula

C21H22O11

Molecular weight

450.39

Purity

98%

Delivery

惯例下常温包邮

Product Description

Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, indicates that marein may be a potent compound for preventing/counteracting diabetic encephalopathy. Marein shows antioxidant activity. Marein can improve insulin resistance induced by high glucose in HepG2 cells through CaMKK/AMPK/GLUT1 to promote glucose uptake, through IRS/Akt/GSK-3β to increase glycogen synthesis, and through Akt/FoxO1 to decrease gluconeogenesis. Marein shows Histone deacetylase enzymes (HDACs) inhibitory activity and it also can inhibit TNFα-induced NF-κB activation.

Technical data and support

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Marein

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