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Pemetrexed

Reference Materials
Item No.CFZ02370
CAS Number:137281-23-3
Purity:98%
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Basic information and product description
CAS number
137281-23-3
Item number
CFZ02370
Chinese name
培美曲塞二钠盐
English name
Pemetrexed
Chinese alias
(N-(4-[2-(2-氨基-4,7-二氢-4-氧-1H-吡咯[2,3-D]嘧啶-5-基)乙基]苯甲酰)-L-谷氨酸
English alias
N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid
SMILES
Chemical name
(2S)-2-[[4-[2-(2-氨基-4-氧代-1,7-二氢吡咯并[2,3-d]嘧啶-5-基)乙基]苯甲酰]氨基]戊二酸
Molecular formula
C₂₀H₂₁N₅O₆‌
Molecular weight
427.41
Purity
98%
Delivery
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Product Description

Pemetrexed 是一种叶酸拮抗剂 (antifolate)。抑制胸苷酸合成酶 (TS),二氢叶酸还原酶 (DHFR) 和甘氨酰胺核苷酸甲酰转移酶 (GARFT),Ki 分别为 1.3 nM,7.2 nM 和 65 nM。

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