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2'-Fluoro-2'-deoxyadenosine

Reference Materials
Item No.CFZ01829
CAS Number:64183-27-3
Purity:98%
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Basic information and product description
CAS number
64183-27-3
Item number
CFZ01829
Chinese name
2'-氟-2'-脱氧腺苷
English name
2'-Fluoro-2'-deoxyadenosine
Chinese alias
(2R,3R,4R,5R)-5-(6-氨基嘌呤-9-基)-4-氟-2-(羟甲基)氧杂环戊烷-3-醇
English alias
(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
SMILES
Chemical name
Molecular formula
C₁₀H₁₂FN₅O₃‌
Molecular weight
269.23
Purity
98%
Delivery
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Product Description

可用于合成可与 RNA 杂交的 2 ' -脱氧-2 ' -氟修饰的寡核苷酸。2′-Deoxy-2′-fluoroadenosine 能被大肠杆菌嘌呤核苷磷酸化酶 (PNP) 有效地裂解成毒性物 2-氟腺嘌呤 (FAde),对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。 

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