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(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine

Reference Materials
Item No.CFZ01639
CAS Number:1223404-88-3
Purity:98%
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Basic information and product description
CAS number
1223404-88-3
Item number
CFZ01639
Chinese name
LOXO101的中间体
English name
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine
Chinese alias
(R)-5-[2-(2,5-二氟苯基)-1-吡咯烷基]吡唑并[1,5-A]嘧啶-3-胺
English alias
(R)-5-(2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-amine
SMILES
Chemical name
(R)-5-(2-(2,5-二氟苯基)吡咯烷-1-基)吡唑并[1,5-a]嘧啶-3-胺
Molecular formula
C₁₆H₁₅F₂N₅
Molecular weight
315.32
Purity
98%
Delivery
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Product Description

该化合物是 ‌拉罗替尼(TRK抑制剂,用于治疗 NTRK 基因融合实体瘤)的合成中间体‌,也被称为“拉罗还原氨基物”或“拉罗替尼杂质6”。

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