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Decitabine

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Item No.02870
CAS Number:2353-33-5
Purity:98%
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Basic information and product description
CAS number
2353-33-5
Item number
02870
Chinese name
地西他滨
English name
Decitabine
Chinese alias
5-氮杂-2-脱氧胞苷;脱氧氮杂胞苷;2-脱氧-5-氮杂胞啶;
English alias
5-Aza-2'-deoxycytidine;5-AZA-CdR;5-Azadeoxycytidine;NSC 127716;NSC-127716;NSC127716;Dacogen;DAC;
SMILES
C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O
Chemical name
Molecular formula
C8H12N4O4
Molecular weight
228.21
Purity
98%
Delivery
惯例下常温包邮
Product Description

地西他滨（NSC 127716；Dacogen；DAC）是一种口服活性脱氧胞苷类似物抗代谢药和DNA甲基转移酶抑制剂。地西他滨代替胞嘧啶掺入DNA中，可以将DNA甲基转移酶共价捕获到DNA中，导致酶的不可逆抑制。地西他滨诱导细胞G2/M期阻滞和细胞凋亡。地西他滨具有强大的抗癌活性。

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