MC-Val-Cit-PAB-Cl

Item No.CFZ02838

CAS Number:1639351-92-0

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

Application of bioactive small molecules in disease research

Green intelligence creates industry trends, Fuzhen Biology promotes low-carbon development of fine chemical industry

The monoclonal antibody industry is developing rapidly, and Fuzhen Biotechnology is improving its supply system for monoclonal antibody related raw materials

The global biopharmaceutical market continues to expand

Molecular building blocks are used as accelerators for the development of new drugs

Basic information and product description

CAS number

1639351-92-0

Item number

CFZ02838

Chinese name

MC-VAL-CIT-PAB-CL

English name

MC-Val-Cit-PAB-Cl

Chinese alias

N-((S)-1-(((S)-1-((4-(氯甲基)苯基)氨基)-1-氧代-5-脲基戊烷-2-基)氨基)-3-甲基-1-氧代丁-2-基)-6-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)己酰胺

English alias

N-((S)-1-(((S)-1-((4-(Chloromethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide

SMILES

Chemical name

Molecular formula

C₂₈H₃₉ClN₆O₆

Molecular weight

591.1

Purity

98%

Delivery

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Product Description

Mc-Val-Cit-PAB-Cl 是一种可降解的 ADC linker，可用于连接 MMAE 和抗体，从而形成抗体-MC-vc-MMAE (如 anti-CD22-MC-VC-PABC-MMAE，对 BJAB 和 WSU 具有细胞毒性，IC50 分别为 3.3 nM 和 0.95 nM)。