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Onjisaponin B

Reference Materials
Item No.CFZ08712
CAS Number:35906-36-6
Purity:98%
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Basic information and product description
CAS number
35906-36-6
Item number
CFZ08712
Chinese name
远志皂苷B
English name
Onjisaponin B
Chinese alias
English alias
Senegin III; Sinegin 3;
SMILES
CC1C(C(C(C(O1)OC2C(C(OC(C2OC3C(C(C(C(O3)C)OC4C(C(C(CO4)OC5C(C(C(C(O5)CO)O)O)O)O)O)O)O)OC(=O)C67CCC(CC6C8=CCC9C(C8(CC7)CO)(CCC1C9(CC(C(C1(C)C(=O)O)OC1C(C(C(C(O1)CO)O)O)O)O)C)C)(C)C)C)OC(=O)C=CC1=CC=C(C
Chemical name
Molecular formula
C75H112O35
Molecular weight
1573.69
Purity
98%
Delivery
惯例下常温包邮
Product Description

Onjisaponin B is extracted from the roots of Polygala tenuifolia. It was able to induce autophagy and accelerate both the removal of mutant huntingtin and A53T α-synuclein, which are highly associated with Huntington disease and Parkinson disease, respectively. It induces autophagy via the AMPK-mTOR signaling pathway. It increased the NGF level and may have potential therapeutic effects for the treatment of Alzheimer disease patients.

Technical data and support
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