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Kakkalide

Reference Materials
Item No.CFZ08568
CAS Number:58274-56-9
Purity:98%
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Basic information and product description
CAS number
58274-56-9
Item number
CFZ08568
Chinese name
葛花甙
English name
Kakkalide
Chinese alias
English alias
SMILES
COC1=CC=C(C=C1)C2=COC3=CC(=C(C(=C3C2=O)O)OC)OC4C(C(C(C(O4)COC5C(C(C(CO5)O)O)O)O)O)O
Chemical name
Molecular formula
C28H32O15
Molecular weight
608.55
Purity
98%
Delivery
惯例下常温包邮
Product Description

Kakkalide is isolated and purified from the roots of Pueraria lobata.Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor. Kakkalide attenuates ethanol-induced gastric injury in mice by inhibiting the infiltration of neutrophils.Kakkalide can inhibit ROS-associated inflammation and ameliorated insulin-resistant endothelial dysfunction by beneficial effects on IRS-1 function. Kakkalide has anti-inflammatory effects, it ameliorates carrageenan-induced inflammation in mice by inhibiting NF-κB pathway. 5. Kakkalide shows protective effects on ethanol-induced lethality and hepatic injury are dependent on its biotransformation by human intestinal microflora.

Technical data and support
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