Isosorbide dinitrate

Item No.CFZ08566

CAS Number:87-33-2

Purity:98%

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PRODUCT CLASSIFICATION

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Basic information and product description

CAS number

87-33-2

Item number

CFZ08566

Chinese name

硝酸异山梨酯

English name

Isosorbide dinitrate

Chinese alias

English alias

NSC 80038; NSC-80038; NSC80038; SST-101; Dilatrate SR; Korodil;

SMILES

C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O[N+](=O)[O-]

Chemical name

Molecular formula

C6H8N2O8

Molecular weight

236.14

Purity

98%

Delivery

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Product Description

Isosorbide dinitrate is an organic nitrate ester and nitric oxide (NO) donor in the same class as nitroglycerin. It induces vasodilation with IC50 values of 0.56 and 1.82 µM for isolated precontracted rabbit femoral vein and artery, respectively. Isosorbide dinitrate increases oxygenation of tumor tissue in vivo in a mouse xenograft model. It also inhibits platelet aggregation in vitro and in vivo at concentrations in the micromolar range. Formulations containing isosorbide dinitrate have been used for the treatment of angina pectoris.

Technical data and support

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Isosorbide dinitrate

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