Monocrotaline

Item No.CFZ08477

CAS Number:315-22-0

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

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Basic information and product description

CAS number

315-22-0

Item number

CFZ08477

Chinese name

野百合碱

English name

Monocrotaline

Chinese alias

English alias

A 6080;A-6080;A6080;

SMILES

CC1C(=O)OC2CCN3C2C(=CC3)COC(=O)C(C1(C)O)(C)O

Chemical name

Molecular formula

C16H24NO6

Molecular weight

325.36

Purity

98%

Delivery

惯例下常温包邮

Product Description

Monocrotaline is a natural ligand that exhibits dose-dependent cytotoxicity as a pyrrolizidine alkaloid and toxic plant constituent; the alkaloid causes pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects.

Technical data and support

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Monocrotaline

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