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Monotropein

Reference Materials
Item No.CFZ08432
CAS Number:5945-50-6
Purity:98%
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Basic information and product description
CAS number
5945-50-6
Item number
CFZ08432
Chinese name
水晶兰甙
English name
Monotropein
Chinese alias
水晶兰苷;
English alias
Monotropeine;
SMILES
C1=CC(C2C1C(=COC2OC3C(C(C(C(O3)CO)O)O)O)C(=O)O)(CO)O
Chemical name
Molecular formula
C16H22O11
Molecular weight
390.34
Purity
98%
Delivery
惯例下常温包邮
Product Description

Monotropein, which comes from the root of Morinda officinalis How, was found to inhibit the expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) mRNA in LPS-induced RAW 264.7 macrophages. The anti-inflammatory effects of monotropein are mainly related to the inhibition of the expressions of inflammatory mediators via NF-κB inactivation, and support its possible therapeutic role in colitis. Monotropein also exerted anti-apoptosis and anti-catabolic activity in chondrocytes.

Technical data and support
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