Icaritin

Item No.CFZ08055

CAS Number:521-45-9

Purity:98%

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PRODUCT CLASSIFICATION

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NEWS

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Basic information and product description

CAS number

521-45-9

Item number

CFZ08055

Chinese name

淫羊藿素

English name

Icaritin

Chinese alias

水合淫羊藿素;巫山淫羊藿素;

English alias

Wushanicaritin;

SMILES

Chemical name

Molecular formula

C21H22O7

Molecular weight

386.4

Purity

98%

Delivery

惯例下常温包邮

Product Description

Icaritin is an oral traditional Chinese medicine, derived from barrenwort, which targets the estrogen receptor α36. IC50 values for Icaritin are 8,13 and 18 μM for K562, CML-CP and CML-BC cells respectively. Icaritin inhibits the invasion and epithelial-to-mesenchymal transition of glioblastoma cells by targeting EMMPRIN via PTEN/AKt/HIF-1α signalling. Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway. Icaritin activates JNK-dependent mPTP necrosis pathway in colorectal cancer cells.

Technical data and support

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Icaritin

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