Plitidepsin

Item No.CFZ08067

CAS Number:137219-37-5

Purity:98%

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PRODUCT CLASSIFICATION

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NEWS

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Basic information and product description

CAS number

137219-37-5

Item number

CFZ08067

Chinese name

普拉泰

English name

Plitidepsin

Chinese alias

去氢代代宁B;普利地新;普立肽;普利地星;

English alias

Dehydrodidemnin B;Aplidine;

SMILES

CCC(C)C1C(CC(=O)OC(C(=O)C(C(=O)NC(C(=O)N2CCCC2C(=O)N(C(C(=O)OC(C(C(=O)N1)NC(=O)C(CC(C)C)N(C)C(=O)C3CCCN3C(=O)C(=O)C)C)CC4=CC=C(C=C4)OC)C)CC(C)C)C)C(C)C)O

Chemical name

Molecular formula

C57H87N7O15

Molecular weight

1110.34

Purity

98%

Delivery

惯例下常温包邮

Product Description

Plitidepsin is a cyclic depsipeptide isolated from the marine tunicate Aplidium albicans. Plitidepsin displays a broad spectrum of antitumor activities, inducing apoptosis by triggering mitochondrial cytochrome c release, initiating the Fas/DC95, JNK pathway and activating caspase 3 activation. This agent also inhibits elongation factor 1-a, thereby interfering with protein synthesis, and induces G1 arrest and G2 blockade, thereby inhibiting tumor cell growth.

Technical data and support

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Plitidepsin

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