Diphyllin

Item No.CFZ08033

CAS Number:22055-22-7

Purity:98%

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PRODUCT CLASSIFICATION

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NEWS

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Basic information and product description

CAS number

22055-22-7

Item number

CFZ08033

Chinese name

二叶草素

English name

Diphyllin

Chinese alias

山荷叶素;双叶茶素;

English alias

SMILES

COC1=C(C=C2C(=C1)C(=C3C(=C2O)COC3=O)C4=CC5=C(C=C4)OCO5)OC

Chemical name

Molecular formula

C21H16O7

Molecular weight

380.35

Purity

98%

Delivery

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Product Description

Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) inhibitor with an IC50 value of 17 nM and inhibits lysosomal acidification in human osteoclasts. Diphyllin inhibits NO production with an IC50 of 50 μM and has anticancer and anti-inflammatory activities.

Technical data and support

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Diphyllin

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