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Epieriocalyxin A

Reference Materials
Item No.CFZ07927
CAS Number:191545-24-1
Purity:98%
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Basic information and product description
CAS number
191545-24-1
Item number
CFZ07927
Chinese name
表毛萼甲素
English name
Epieriocalyxin A
Chinese alias
English alias
SMILES
CC1C2CCC3C(C2)(C1=O)C(=O)OCC34C(C(C=CC4=O)(C)C)C=O
Chemical name
Molecular formula
C20H24O5
Molecular weight
344.4
Purity
98%
Delivery
惯例下常温包邮
Product Description

Epieriocalyxin A, a diterpenoid isolated from I. eriocalyx, suppressed Caco-2 colon cancer cell growth. Western blot results showed that both JNK and ERK1/2 activation was decreased after Epieriocalyxin A treatment in a dose-dependent manner. Epieriocalyxin A increased the expression of caspase 3 and Bax, and decreased Bcl2 expression. Our results suggest that Epieriocalyxin A is a novel compound that induces colon cancer apoptosis. Epieriocalyxin A could be a potential drug for colon cancer therapy in the future.

Technical data and support
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