Raloxifene 6-Glucuronide

Item No.CFZ07865

CAS Number:174264-50-7

Purity:98%

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PRODUCT CLASSIFICATION

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Basic information and product description

CAS number

174264-50-7

Item number

CFZ07865

Chinese name

雷洛昔芬-6-葡萄糖醛酸苷

English name

Raloxifene 6-Glucuronide

Chinese alias

雷洛昔芬-D4-6-葡萄糖醛酸苷;

English alias

Ral-6-Gluc;

SMILES

C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)OC5C(C(C(C(O5)C(=O)O)O)O)O)C6=CC=C(C=C6)O

Chemical name

Molecular formula

C34H35NO10S

Molecular weight

649.71

Purity

98%

Delivery

惯例下常温包邮

Product Description

Raloxifene 6-glucuronide is a primary metabolite of Raloxifene. Raloxifene 6-glucuronide is mediated mostly by UGT1A1 and UGT1A8. Raloxifene 6-glucuronide binds to estrogen receptor with an IC50 of 290 μM. Raloxifene is a selective and nonsteroidal estrogen receptor modulator. Raloxifene activates TGFβ3 promoter as a full agonist at nanomolar concentrations, and inhibits the estrogen response element-containing vitellogenin promoter expression.

Technical data and support

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Raloxifene 6-Glucuronide

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