Radicicol

Item No.CFZ07780

CAS Number:12772-57-5

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

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Basic information and product description

CAS number

12772-57-5

Item number

CFZ07780

Chinese name

根赤壳菌素

English name

Radicicol

Chinese alias

根赤壳霉素;单孢菌素 A;

English alias

Monorden;Monorden A;

SMILES

CC1CC2C(O2)C=CC=CC(=O)CC3=C(C(=CC(=C3Cl)O)O)C(=O)O1

Chemical name

Molecular formula

C18H17ClO6

Molecular weight

364.78

Purity

98%

Delivery

惯例下常温包邮

Product Description

Radicicol is an inhibitor of Hsp90 with an IC50 value < 1 μM, and leads to proteasomal degradation. Radicicol exhibits inhibition on PDK with IC50s of 230 μM (PDK1) and 400 μM (PDK3). Radicicol is an antifungal and antimalarial antibiotic, impairs mitochondrial replication by targeting P. falciparum topoisomerase VIB. Radicicol is also an inhibitor of fat mass and obesity-associated protein (FTO), with an IC50 value of 16.04 μM.

Technical data and support

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Radicicol

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