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Demethylnobiletin

Reference Materials
Item No.CFZ07755
CAS Number:2174-59-6
Purity:98%
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Basic information and product description
CAS number
2174-59-6
Item number
CFZ07755
Chinese name
去甲基川陈皮素
English name
Demethylnobiletin
Chinese alias
5-去甲基川陈皮素;5-羟基川陈皮素;
English alias
5-O-Demethylnobiletin;5-Demethylnobiletin;
SMILES
COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)OC)OC)O)OC
Chemical name
Molecular formula
C20H20O8
Molecular weight
388.37
Purity
98%
Delivery
惯例下常温包邮
Product Description

Demethylnobiletin, a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM.

Technical data and support
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