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Phenethyl caffeate

Reference Materials
Item No.CFZ07739
CAS Number:104594-70-9
Purity:98%
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Basic information and product description
CAS number
104594-70-9
Item number
CFZ07739
Chinese name
咖啡酸苯乙酯
English name
Phenethyl caffeate
Chinese alias
咖啡酸β-苯乙醇酯;
English alias
Caffeic acid phenethyl ester;Phenylethyl caffeate;
SMILES
C1=CC=C(C=C1)CCOC(=O)C=CC2=CC(=C(C=C2)O)O
Chemical name
Molecular formula
C17H16O4
Molecular weight
284.31
Purity
98%
Delivery
惯例下常温包邮
Product Description

Caffeic Acid Phenethyl Ester is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis, with antineoplastic, cytoprotective and immunomodulating activities. Upon administration, caffeic acid phenethyl ester (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).

Technical data and support
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