PF-06700841 P-Tosylate

Item No.CFZ01327

CAS Number:2140301-96-6

Purity:98%

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PRODUCT CLASSIFICATION

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NEWS

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Basic information and product description

CAS number

2140301-96-6

Item number

CFZ01327

Chinese name

PF-06700841 P-Tosylate

English name

PF-06700841 P-Tosylate

Chinese alias

(1S)-2,2-二氟环丙基][3-[2-[(1-甲基-1H-吡唑-4-基)氨基]-4-嘧啶基]-3,8-二氮杂双环[3.2.1]辛8-基]甲酮对甲苯磺酸盐

English alias

(1S)-2,2-Difluorocyclopropyl][3-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-3,8-diazabicyclo[3.2.1]oct-8-yl]methanone tosylate

SMILES

Chemical name

Molecular formula

C25H29F2N7O4S

Molecular weight

561.61

Purity

98%

Delivery

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Product Description

Brepocitinib (PF-06700841) P-Tosylate 是一种有效的 JAK1 和 TYK2 双重抑制剂， IC50 值分别为 17 nM 和 23 nM。Brepocitinib P-Tosylate 还分别以 IC50 值为 77 nM 和 6.49 μM 抑制 JAK2 和 JAK3。

Technical data and support

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PF-06700841 P-Tosylate

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