NVS-SM1

Item No.CFZ01231

CAS Number:1562338-42-4

Purity:98%

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PRODUCT CLASSIFICATION

News

NEWS

Application of bioactive small molecules in disease research

Green intelligence creates industry trends, Fuzhen Biology promotes low-carbon development of fine chemical industry

The monoclonal antibody industry is developing rapidly, and Fuzhen Biotechnology is improving its supply system for monoclonal antibody related raw materials

The global biopharmaceutical market continues to expand

Molecular building blocks are used as accelerators for the development of new drugs

Basic information and product description

CAS number

1562338-42-4

Item number

CFZ01231

Chinese name

NVS-SM1

English name

NVS-SM1

Chinese alias

5-(1H-吡唑-4-基)-2-(6-((2,2,6,6-四甲基哌啶-4-基)氧基)哒嗪-3-基)苯酚

English alias

5-(1H-Pyrazol-4-yl)-2-(6-((2,2,6,6-tetramethylpiperidin-4-yl)oxy)pyridazin-3-yl)phenol

SMILES

Chemical name

Molecular formula

C₂₂H₂₇N₅O₂

Molecular weight

393.48

Purity

98%

Delivery

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Product Description

Branaplam (LMI070; NVS-SM1) 是一种口服有效和选择性的 SMN2 拼接调节剂，对 SMN 的 EC50 为 20 nM。Branaplam 抑制 hERG，IC50 为 6.3 μM。Branaplam 在严重的脊髓性肌萎缩症 (SMA) 小鼠模型中可提高全长 SMN 蛋白并延长其生存期。

Technical data and support

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NVS-SM1

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