Kainic acid is a naturally occurring neuroexcitatory amino acid. It is a selective agonist for a subtype of ainate-class ionotropic glutamate receptor found in seaweed. It increases production of mitochondrial dysfunction, reactive oxygen species and apoptosis in neurons in many regions of the brain. It increases glutamate release and stimulates Na channels, inducing epileptic seizures and neurocytosis (apoptosis). It has been used to study mechanisms of apoptosis and epilepsy.
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