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Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural polyphenol derived from red wine; in Asian folk-medicine it and it’s glycoside, polydatin (sc-203203) are the primary ingredients of Kojo-Kon (derived from the dried root of Japanese knotweed). This trihydroxystilbene is derived from various sources and has been studied with regard to numerous applications including reducing serum lipids, inhibition of platelet aggregation, and actions as a chemopreventative agent and antioxidant. Resveratrol has been shown to increase the longevity of yeast as well as having antiproliferative on cancer stem cells. Resveratrol is a specific inhibitor of Cox-1 (cyclooxygenase-1) via inhibition of the hydroperoxidase activity of Cox-1.
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