Vitexin is a class of nature lignan compounds isolated from the seeds of Vitex trifolia L. What different from the classic lignans is its action and anticancer effect is mediated by the mechanisms, vitexin-induced antitumor effect and cytotoxic activity is exerted through proapoptotic process, which is mediated by a decreased Bcl-2/Bax ratio and activation of caspases.Vitexin inhibits the activities of anti-nociceptive, anti-spasmodic and anti-oxidant.
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