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21-Deoxycortisone

Reference Materials
Item No.CFZ07885
CAS Number:1882-82-2
Purity:98%
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Basic information and product description
CAS number
1882-82-2
Item number
CFZ07885
Chinese name
21-去氧可的松
English name
21-Deoxycortisone
Chinese alias
17α-羟基孕甾-4-烯-3,11,20-三酮;
English alias
21-Deoxy Cortisone;17-Hydroxypregn-4-ene-3,11,20-trione;
SMILES
CC(=O)C1(CCC2C1(CC(=O)C3C2CCC4=CC(=O)CCC34C)C)O
Chemical name
Molecular formula
C21H28O4
Molecular weight
344.44
Purity
98%
Delivery
惯例下常温包邮
Product Description

21-Deoxycortisone is a corticosteroid metabolite of 11-keto progesterone. It is formed from 11-keto progesterone by the cytochrome P450 (CYP) isoform CYP17A1, but can also be produced via oxidation of 21-deoxycortisol by 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). Levels of 21-deoxycortisone are increased in patients with congenital adrenal hyperplasia, an inborn error of metabolism characterized by a deficiency in 21-hydroxylase.

Technical data and support
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